The acoustic characteristics of continuous speech produced by an adult male talker with and without oral (nerve block) anesthesia were investigated using digital speech processing procedures. Vowel-to-consonant ratios, long-time and short-time spectra, fundamental frequency distributions, phonation-time ratios, and rate of utterances were calculated and compared for the normal and anesthetized conditions. The results showed that the speech produced without oral sensation was characterized by a reduction and shift of high-frequency energy, temporal disorganization primarily manifested as prolongation of utterance, and higher and more variable fundamental frequencies. The study also demonstrated applicability of computer techniques on general acoustic analysis of continuous speech.