Language Development and Brain Magnetic Resonance Imaging Characteristics in Preschool Children With Cerebral Palsy Purpose The purpose of this study was to investigate characteristics of language development in relation to brain magnetic resonance imaging (MRI) characteristics and the other contributing factors to language development in children with cerebral palsy (CP). Method The study included 172 children with CP who underwent brain MRI ... Research Article
Research Article  |   May 24, 2017
Language Development and Brain Magnetic Resonance Imaging Characteristics in Preschool Children With Cerebral Palsy
 
Author Affiliations & Notes
  • Ja Young Choi
    Department of Rehabilitation Medicine, Severance Hospital, Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea
  • Yoon Seong Choi
    Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
  • Eun Sook Park
    Department of Rehabilitation Medicine, Severance Hospital, Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea
  • Disclosure: The authors have declared that no competing interests existed at the time of publication.
    Disclosure: The authors have declared that no competing interests existed at the time of publication. ×
  • Correspondence to Eun Sook Park: pes1234@yuhs.ac and 0275502@yuhs.ac
  • Editor: Sean Redmond
    Editor: Sean Redmond×
  • Associate Editor: Steve Small
    Associate Editor: Steve Small×
Article Information
Development / Special Populations / Genetic & Congenital Disorders / Attention, Memory & Executive Functions / Language / Research Articles
Research Article   |   May 24, 2017
Language Development and Brain Magnetic Resonance Imaging Characteristics in Preschool Children With Cerebral Palsy
Journal of Speech, Language, and Hearing Research, May 2017, Vol. 60, 1330-1338. doi:10.1044/2016_JSLHR-L-16-0281
History: Received July 6, 2016 , Revised September 21, 2016 , Accepted November 21, 2016
 
Journal of Speech, Language, and Hearing Research, May 2017, Vol. 60, 1330-1338. doi:10.1044/2016_JSLHR-L-16-0281
History: Received July 6, 2016; Revised September 21, 2016; Accepted November 21, 2016

Purpose The purpose of this study was to investigate characteristics of language development in relation to brain magnetic resonance imaging (MRI) characteristics and the other contributing factors to language development in children with cerebral palsy (CP).

Method The study included 172 children with CP who underwent brain MRI and language assessments between 3 and 7 years of age. The MRI characteristics were categorized as normal, malformation, periventricular white matter lesion (PVWL), deep gray matter lesion, focal infarct, cortical/subcortical lesion, and others. Neurodevelopmental outcomes such as ambulatory status, manual ability, cognitive function, and accompanying impairments were assessed.

Results Both receptive and expressive language development quotients (DQs) were significantly related to PVWL or deep gray matter lesion severity. In multivariable analysis, only cognitive function was significantly related to receptive language development, whereas ambulatory status and cognitive function were significantly associated with expressive language development. More than one third of the children had a language developmental discrepancy between receptive and expressive DQs. Children with cortical/subcortical lesions were at high risk for this discrepancy.

Conclusions Cognitive function is a key factor for both receptive and expressive language development. In children with PVWL or deep gray matter lesion, lesion severity seems to be useful to predict language development.

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