Longitudinal Phonatory Characteristics After Botulinum Toxin Type A Injection Following Botulinum Toxin Type A injection, glottal competency of an adductor spasmodic dysphonia patient is thought to vary over a wide range. This study quantifies variability in laryngeal adduction for one such patient over a 10-week period. Analyses of kinematic and aerodynamic measures were used to track the voice weekly. ... Research Article
Research Article  |   October 01, 1996
Longitudinal Phonatory Characteristics After Botulinum Toxin Type A Injection
 
Author Affiliations & Notes
  • Kimberly V. Fisher
    University of Oklahoma Health Sciences Center Oklahoma City
  • Ronald C. Scherer
    Denver Center for the Performing Arts Denver, CO
  • Chwen G. Guo
    Denver Center for the Performing Arts Denver, CO
  • Ann S. Owen
    University of Oklahoma Health Sciences Center Oklahoma City
  • Contact author: Kimberly V. Fisher, PhD, Department of Communication Sciences and Disorders, Northwestern University, 2299 North Campus Drive, Evanston, IL 60208-3507. Email: kfi663@nwu.edu
  • Currently affiliated with Northwestern University, Evanston, IL
    Currently affiliated with Northwestern University, Evanston, IL×
Article Information
Speech, Voice & Prosody / Speech / Research Articles
Research Article   |   October 01, 1996
Longitudinal Phonatory Characteristics After Botulinum Toxin Type A Injection
Journal of Speech, Language, and Hearing Research, October 1996, Vol. 39, 968-980. doi:10.1044/jshr.3905.968
History: Received March 20, 1996 , Accepted April 18, 1996
 
Journal of Speech, Language, and Hearing Research, October 1996, Vol. 39, 968-980. doi:10.1044/jshr.3905.968
History: Received March 20, 1996; Accepted April 18, 1996

Following Botulinum Toxin Type A injection, glottal competency of an adductor spasmodic dysphonia patient is thought to vary over a wide range. This study quantifies variability in laryngeal adduction for one such patient over a 10-week period. Analyses of kinematic and aerodynamic measures were used to track the voice weekly. The measures included the electroglottographic waveform width (EGGW50), nondimensional electroglottographic slope quotient (SLQ), glottal flow open quotient (FOQ), dc glottal flow, and nondimensional glottal flow peak quotient (FPQ). The results suggested that change in degree of glottal adduction over time can be observed even when vocal instability is present within each recording session. Perceptual ratings of vocal quality (breathy to pressed) were related to the laryngeal measures. The coefficient of variation for EGGW50 and the percentage of dichrotic phonations reached minima during sessions with predominantly breathy and hypoadducted phonation. The methods used in this study show potential to aid decisions about dose level and sources of perceptual adductor spasmodic dysphonia symptoms for a given patient.

Acknowledgments
The authors wish to acknowledge Willis Owen and Paul Swank for statistical consultation. This work was supported in part by research grants P60 DC00976 from the National Institute on Deafness and Other Communication Disorders, National Institutes of Health; HN-031 of The Oklahoma Center for the Advancement of Science and Technology; and The American Speech and Hearing Foundation.
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