The Effects of Triamcinolone Acetonide on the Voice With the exception of the pioneering work by Damsté in the mid 1960’s and early '70’s, no long term quantitative research on voice changes subsequent to drug therapy has been reported. This study reports the effects of a specific cortico-steroid, triamcinolone acetonide, on selected aerodynamic and acoustic parameters reflecting the ... Research Article
Research Article  |   September 01, 1979
The Effects of Triamcinolone Acetonide on the Voice
 
Author Affiliations & Notes
  • Kenneth L. Watkin
    University of Michigan, Ann Arbor
  • Stanley J. Ewanowski
    University of Wisconsin, Madison
Article Information
Research Articles
Research Article   |   September 01, 1979
The Effects of Triamcinolone Acetonide on the Voice
Journal of Speech, Language, and Hearing Research, September 1979, Vol. 22, 446-455. doi:10.1044/jshr.2203.446
History: Received April 24, 1978 , Accepted October 18, 1978
 
Journal of Speech, Language, and Hearing Research, September 1979, Vol. 22, 446-455. doi:10.1044/jshr.2203.446
History: Received April 24, 1978; Accepted October 18, 1978

With the exception of the pioneering work by Damsté in the mid 1960’s and early '70’s, no long term quantitative research on voice changes subsequent to drug therapy has been reported. This study reports the effects of a specific cortico-steroid, triamcinolone acetonide, on selected aerodynamic and acoustic parameters reflecting the vocal performance of twenty-one chronic asthmatic steroid dependent individuals. Measurements of the subjects' vocal fundamental frequency, maximum phonation time, oral air volume velocity, and peak intra-oral air pressure during production of selected speech stimuli were made before the introduction of triamcinolone and following the first and second years of drug use. After two years of triamcinolone therapy, significant changes were noted in parameters reflecting laryngeal functioning. Respiratory performance remained unchanged for most subjects. The results are discussed in terms of the possible physiological changes that might have occurred and their implications for the speech-language pathologist and speech scientist in medical management.

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